Contents

• List of Tables
• List of Figures
• Introduction
  • Basic definitions
  
  
• History of transplantation
  • Timeline
  • People in transplantation
  
  
• Models used to study transplantion
  • Mice
  • Cats
  • Dogs
  • Rabbits
  • Hamsters
  • Humans
  
  
• Immune response to transplantation
  • First and second set response
  • Tenets of transplantation immunology
  • Genes responsible for rejection
  • Major Histocompatibiliy Complex/Human Leucocyte Antigens
  • Minor Histocompatibility Complex
  • Cells of the immune response
  • Basis of rejection
  • Patterns of rejection
  
  
• Causes of end stage renal failure
• Renal replacement therapy
• Problems in people on long term dialysis
  • Amyloidosis
  • Acquired cystic disease
  
  
• Organisation of the renal transplant team
  • What happens when a potential donor is identified?
  
  
• The donor
  • Selection criteria for donors
  • Medical history of the donor
  • Blood tests on the donor
  
  
• Multi organ retrieval
  • Sequence of retreival
  • Initial incision
  • Cannulation of great vessels
  • Heart and lung retreival
  • Liver retreival
  • Pancreatic retreival
  • Kidney retreival
  
  
• Selection of the patient for renal transplantation
  • End stage renal failure
  • Similar tissue type
  
  
• Transplantation of the kidney
  • Prepartion of the donor kideny
  • Insertion of the donor kidney
  • Variations on the theme
  
  
• Drugs
  • Immunosupressant drugs
  • Compliance with immunosuppressant therapy
  • Anti viral therapy
  • Recombinant Erythropoietin
  
  
• Care of the patient post renal transplantion
  • An immunosuppressant regimen
  
  
• Important facts and figures
  • Rate of development of end stage renal failure
  • Rate of transplantation
  • Survival rate of renal transplants, people post transplantation and in those on dialysis
  • Complications
  
  
• Does renal transplantation improve quality of life?
• Glossary
  • Allograft
  • Autograft
  • Isograft
  • Major Histocompatibility Complex
  • Minor Histocompatibility Complex
  • Organ
  • Syngraft
  • Tissue
  • Xenograft
  
  
• Abbreviations
• Bibliography
• Index