Daily 6 hour infusions should continue until it is clinically appropriate to stop From experience with Iloprost, the following is an appropriate treatment guide
| Disease | No. of days of infusion (6 hours per day) |
| Raynaud's syndrome | 3-5 |
| Severe Raynaud's syndrome (with digital ulcers) | 5-7 |
| Ischaemic rest pain (without necrosis/ulceration) Diabetic/non diabetic | 14-21 |
| Ischaemic ulceration Diabetic/non diabetic | 21-28 |
| Following amputation for ischaemia | 14-21 |
| Buerger's disease (with or without ulceration) | 21-28 |
Infusions can be continued beyond these recommendations if thought beneficial.
500ml Infusion Fluid Flow Rates for 0.1 millegrammes Iloprost in 500ml infusion fluid Weight (kg) 40 45 50 55 60 65 70 75 80 85 90 Dose Iloprost ng/kg/min Flow rates ml/hr 10.0 120 135 150 165 180 195 210 225 240 255 270 7.5 90 101 113 124 135 146 158 169 180 191 203 5.0 60 68 75 83 90 98 105 113 120 128 135 4.5 54 61 68 77 81 88 95 101 108 115 122 4.0 48 54 60 66 72 78 84 90 96 102 108 3.5 42 47 53 58 63 68 74 79 84 89 95 3.0 36 41 45 50 54 59 63 68 72 77 81 2.5 30 34 38 41 45 49 53 56 60 64 68 2.0 24 27 30 33 36 39 42 45 48 51 54 1.5 18 20 23 25 27 29 32 34 36 38 41 1.0 12 14 15 17 18 20 21 23 24 26 27 0.5 6 7 8 8 9 10 11 11 12 13 14