The Skin

Last updated (19 November 2003)

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What adjuvant therapy should be considered?
Radiation to the draining lymph nodes.
Topical 5-FU
Systemic 5-FU
BCG
Antibodies against Epithelial Growth Factor Receptor

The answer

None of the above are correct

What the student might say

No adjuvant therapy is required. The patient should attend for careful clinical follow up with particular attention to the site of the lesion and examination of the draining lymph node basins. If the lymph nodes become enlarged then it may be necessary to consider a block dissection.

Small Print

There is no evidence that adjuvant radiotherapy to the draining lymph nodes is of any benefit.

Neither topical or systemic 5-fluro-uracil is beneficial in the adjuvant setting.

BCG is of no benefit in squamous cancer of the skin. It is used to treat patients with bladder cancer.

Antibodies designed to block the epidermal growth factor receptor have been found to be useful in patients with certain types of breast cancer. To date there is no evidence that they are of any use in squamous skin cancer.


Adrian P. Ireland